primobolan depot side effects

Afobazol® – a derivative of 2-mercaptobenzimidazole, selective primobolan depot side effects, not belonging to the class of benzodiazepine receptor agonists. It prevents the development of membranozavisimyh changes in the GABA receptor.

Afobazol® possesses primobolan depot side effects effects with an activating component, are not accompanied by gipnosedativny effects (sedation detected in AFOBAZOLA® at doses 40-50 times higher than the ED 50 for the primobolan depot side effects effect). There are no muscle relaxant properties of the drug, a negative impact on memory and attention indicators. If its application is not formed drug dependence and withdrawal symptoms do not develop. The drugs are sold mainly in the form of a combination of primobolan depot side effects (antianxiety) and easily stimulating (activating) effects.

Reducing or eliminating anxiety (concern, foreboding, fear, irritability), strength (fearfulness, tearfulness, anxiety, inability to relax, insomnia, fear), and thus somatic (muscular, sensory, cardiovascular, respiratory, gastrointestinal symptoms ), autonomic (dry mouth, sweating, dizziness), cognitive (difficulty concentrating, impaired memory) violations observed at 5-7 days of treatment AFOBAZOLOM®. The maximum effect is achieved by the end of 4 weeks of treatment and stored in posleterapevticheskom average period of 1-2 weeks. Especially shows the use of the drug in patients with predominantly asthenic personality traits as alarming suspiciousness, insecurity, increased vulnerability and emotional lability, tendency to emotional stress hazardous reactions.Afobazol® toxic (LD 50 in rats is 1.1 g at ED 50 0.001 g).

Pharmacokinetics
The half-life AFOBAZOLA® ingestion of 0.82 hours, the mean maximum concentration (Cmax) – 0,130 ± 0,073 g / ml; mean residence time of the drug in the organism (MRT) – 1,60 ± 0,86 h. Afobazol® distributed extensively on well vascularized organs.

Indications
Afobazol® used in adults with anxiety: generalized anxiety disorder, neurasthenia, adjustment disorder, in patients with various medical conditions (asthma, irritable bowel syndrome, systemic lupus erythematosus, ischemic heart disease, hypertension, arrhythmias), dermatological , cancer and others. diseases. In the treatment of sleep disorders associated with anxiety, neuro dystonia, premenstrual syndrome, alcohol absistentnogo syndrome, to facilitate withdrawal for smoking cessation.

Contraindications
Pregnancy, lactation. Individual intolerance to the drug. Children under 18 years old.

Dosage and administration
Used inside after eating. The optimal single dose – 10 mg daily – 30 mg, distributed into 3 doses during the day. The duration of a course of the drug is 2-4 weeks. If necessary, the daily dose can be increased to 60 mg, and the duration of the treatment and 3 months.

Side effects
Individual hypersensitivity, allergic reactions are possible.

Overdose
If overdose of large and intoxication may develop sedation and increased sleepiness without manifestations of muscle relaxation. As used emergency caffeine sodium benzoate 20% solution in vials of 1.0 ml 2-3 times a day subcutaneously.

Interaction with other drugs
Afobazol® no effect on the narcotic effect of ethanol, and the hypnotic effect of thiopental. Potentiates the anticonvulsant effect of carbamazepine. It is strengthening the primobolan depot side effects effect of diazepam.

Product form
10 tablets or 25 tablets in blisters of PVC film and aluminum foil.

At 30.50, or 100 tablets in a polymer jar complete with lids. Each bank or 3, 5 or 10 contour packs of 10 tablets, or 2 or 4-outline package 25 tablets together with instructions for use in a stack of cardboard. testosterone replacement lumigan before and after diet dr simeon

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