Aurobin ® . – Combination product for the treatment of inflammatory diseases of the anogenital prednisolone kapronat is a non-halogenated glucocorticosteroid. It provides local anti-allergic and anti-inflammatory effect. The drug reduces the permeability of blood vessels, increases the tone of vascular walls, reduces the symptoms of inflammation. Lidocaine – a local anesthetic, quickly eliminates the pain and burning sensation.Panthenol – promotes regeneration of diseased epithelium and mucosa. Triclosan – is an antiseptic broad-spectrum, which acts on the bacteria and fungi.Pharmacokinetics not studied
processes accompanied by inflammation of the perianal area anus itching, eczema and dermatitis, perianal region, cracks, hemorrhoids, anal fistula.
Hypersensitivity to the components of the drug.
The drug should not be used for the treatment of the eyes or periorbital area.
Bacterial, viral or fungal infections of the skin.
Concomitant use of lidocaine for other indications.
Children under the age of 1 year.
Use during pregnancy and lactation
There are no adequate data on the safe use of the drug in pregnant women, so in the first trimester of pregnancy, the drug should not be used. In the second and third trimesters of pregnancy in the appbayer primobolan depot of the drug should be carefully weigh the benefits and risks. Lactation: Corticosteroids and lidocaine get into breast milk, therefore during lactation is necessary to resolve the issue of termination of breastfeeding.
DOSAGE AND ADMINISTRATION
Outwardly, rectal. Adults, elderly patients: The bayer primobolan depot is applied to the affected area 2-4 times a day. If the internal hemorrhoids, a small amount of bayer primobolan depot (pea-sized) is inserted into the rectum 2-4 times per day. With a decrease in the symptoms of the drug can be used frequently. Course of treatment 5-7 days. Children: . Children under 12 months can not apply bayer primobolan depot When using the drug in children should avoid prolonged use of it and over a large surface, regardless of age.
The use of local corticosteroids can cause primarily local side effects: impaired wound healing, burning sensation, itching, irritation, dryness, thinning of the skin, increased sensitivity of the skin.
With long-term use of glucocorticoids – skin atrophy, local hirsutism, telangiectasia, purpura, hypopigmentation , hypertrichosis, folliculitis, acneform rashes, fungal infections, allergic contact dermatitis, diaper rash.
When applied to large surfaces – the system of side effects glucocorticosteroid (stunting, Cushing’s syndrome, benign intracranial hypertension after treatment, hyperglycemia, glycosuria, hypokalemia, increased blood pressure)
long-term use, and a large area due to the systemic effects of lidocaine may cause bradycardia.
Acute overdose is unlikely, however, in the case of overdose or abuse chronic application of the drug may occur by symptoms of systemic action glucocorticosteroid and bradycardia, excessive addition of the drug in the rectum (due lidocaine) when it is necessary to stop treatment or reduce the dose gradually.
Interactions with other drugs
are not known The local application of the drug drug interactions.
should be avoided wherever possible long-term treatment, especially in children, due to possible adrenal suppression. The drug can be used in children with caution, in the minimum dose that provides a therapeutic effect. Duration of therapy in children should not exceed 5 days.
It is necessary to avoid accidental contact with the drug in the eyes or on the periorbital region.
In case of contact should be rinsed with water.
The development and dissemination of secondary infection requires withdrawal of the drug and the appbayer primobolan depot of an antimicrobial or antifungal therapy. Bacterial infection is maintained in warm humid conditions, so the skin should be cleaned before each application of bayer primobolan depot.
Drawing on an extensive surface, or use for a long time can lead to systemic absorption of the active ingredients. With prolonged use of the drug in one region may cause skin atrophy, especially in young people.
Effect on ability to drive and working mechanisms
There are no data on the effect of Aurobin ® affects the ability to transport or driving to work in conditions of increased attention.
bayer primobolan depot for rectal and topical.
In 20 grams of the drug in an aluminum tube. On 1 tuba together with instructions for use in a cardboard box.